The most frequent occurring are pulmonary stenosis (PS) and hypertrophic cardiomyopathy. Of all patients with Noonan syndrome, 50-90% have one or more congenital heart defects. Raaijmakers, R Noordam, C Noonan, J A Croonen, E A van der Burgt, C J A M Draaisma, J M T All rights reserved.Īre ECG abnormalities in Noonan syndrome characteristic for the syndrome? ECG findings are related to the amount and area of damage as indicated by LGE, which confirms the important clinical role of ECG. However, similar to suspected acute myocardial infarction, a normal ECG does not rule out myocarditis. ECG abnormalities can be found in most patients with biopsy proven viral myocarditis at initial presentation. Four of five patients with Q-waves had severe and almost transmural LGE in the lateral wall. Bundle-branch-block occurred more often in patients with septal LGE (11/17). In patients with septal LGE ST- abnormalities were more frequently located in anterolateral leads compared to patients with lateral LGE, in whom ST- abnormalities were most frequently observed in inferolateral leads. Atrial fibrillation was present in 6%, and AV-Block in two patients. In this group, ST- abnormalities were detected most frequently (69%), followed by bundle-branch-block in 26%, and Q-waves in 8%. Sixty-five patients with biopsy proven myocarditis had abnormal ECGs upon admission (77%). Eighty-four consecutive patients fulfilled the following criteria: (1) newly diagnosed biopsy proven viral myocarditis, and (2) non-ischemic LGE, and (3) standard 12-lead- ECG upon admission. Prevalence and type of ECG abnormalities in patients presenting biopsy proven myocarditis, as well as any relation between ECG abnormalities and the in vivo pattern of myocardial damage are unknown. We sought (1) to assess prevalence and type of ECG abnormalities in patients with biopsy proven myocarditis and signs of myocardial damage indicated by LGE, and (2) to evaluate whether ECG abnormalities are related to the pattern of myocardial damage. ECG findings in comparison to cardiovascular MR imaging in viral myocarditis.ĭeluigi, Claudia C Ong, Peter Hill, Stephan Wagner, Anja Kispert, Eva Klingel, Karin Kandolf, Reinhard Sechtem, Udo Mahrholdt, Heiko
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